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Effect of Sub Lethal Doses of Thiamethoxam (A Pesticide) on Hemato-Biochemical Values in Cockerels
 
Shafia Tehseen Gul1, Ahrar Khan1*, Muhammad Farooq1, Shoaib Niaz1, Maqbool Ahmad2, Aisha Khatoon1, Riaz Hussain3, Muhammad Kashif Saleemi1 and Mohammad Farooque Hassan4
 
1Department of Pathology; 2Department of Theriogenology, University of Agriculture, Faisalabad-38040; Pakistan 3University College of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, 63100, Pakistan 4Shaheed Benazir Bhutto University of Veterinary and Animal Sciences, Sakrand, Sindh, Pakistan
*Corresponding author: ahrar1122@uaf.edu.pk
 

Abstract   

The objective of the current study was to find out the toxic effects of sub lethal doses of thiamethoxam on adult poultry birds. For this purpose, a total of 40 cockerels having an age of about 14 weeks were procured from local market and divided into five equal groups. Birds were kept in wire cages under standard management conditions. Birds were given Thaimethoxam @ 250, 500, 750 and 1000mg/kg BW to group A, B, C and D, respectively. Group E served as a control. Blood and serum samples were collected at 15th and 30th day of experiment and analyzed for the various hematological (TEC, TLC, Hb and PCV) and biochemical parameters (total proteins, albumin, globulin, creatinine, blood urea, ALT and AST). The data thus collected were subjected to ANOVA through M-Stat software. Results thus obtained indicated that the sub lethal doses of thiamethoxam reduced significantly (P≤0.05) the hematological values including TEC, Hb, PCV and TLC in a dose dependant manner. The biochemical parameters like total proteins, albumin and globulin were significantly affected by the thiamethoxam. As the dose of the thiamethoxam was increased, these parameters decreased significantly as compared to control group. On the other hand, the values of enzymes ALT and AST were significantly higher in treated groups.

Key words: Cockerels, Enzymes, Hematology, Thaimethoxam, Total proteins

 
   

ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)



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