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THERAPEUTIC DRUG TRIAL IN ALBINO MICE AGAINST  TRYPANOSOMIASIS
S. Ahmad, A. A. Nasir and A.H. Awan
Veterinary Research Institute, Ghazi Road, Lahore Cantt, Pakistan 

Abstract

This study was conducted to determine the trypanocidal efficacy of Antrycide, Fatrybanil and Trypamedium in albino mice experimentally infected sub-cutaneously with Trypanosoma evansi. For this purpose, 25 albino mice were randomly divided into five equal groups i.e. A, B, C, D and E. Groups A, B and C were infected and  then treated with Antrycide, Fatrybanil and Trypamedium, respectively. Group D was kept as infected and group E non-infected control. On the basis of blood smear examination, the efficacy of Antrycide and Fatrybanil was found 100% when used in single dose as compared to Trypamedium which was 100% effective with second dose.

Key words: Trypanosomes, albino mice, Antrycide, Fatrybanil, Trypamedium
 
   

ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)



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