COMPARATIVE EFFICACY OF DETOMIDINE ANDDETOMIDINE - KETAMINE COCKTAIL IN QUAILS
U. F. Durrani, M. Ashraf and A. Khalid¹
Department of Pharmacology and
Toxicology and ¹Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore, Pakistan
Abstract
Twenty adult healthy quails (Coturnix
coturnix) were divided into two equal groups. One group was administered
detomidine (2.4 mg/kg, I/M) and other group was administered detomidine-ketamine
cocktail (1.2 mg/kg + 30 mg/kg, I/M). Detomidine slowly and smoothly induced a
light sedation accompanied by superficial analgesia, hypoventilation,
hypothermia and bradycardia in all birds. Detomidine-ketamine cocktail rapidly
and smoothly induced a deep anaesthesia accompanied by deep analgesia,
hypoventilation, hypothermia and bradycardia and complete loss of all reflexes
in all birds. In both groups, recovery from sedation and anaesthesia was smooth
and of short duration. From this study it was concluded that for minor and least
painful procedures in quails detomidine can be used alone, while for major and
painful surgical procedures detomidine-ketamine combination should be preferred.