EFFECT OF SELENIUM SUPPLEMENTATION ON ANTIBODY TITRES AGAINST
INFECTIOUS BURSAL DISEASE VACCINE IN BROILER CHICKS
M. Arshad, M. Siddique, M. Ashraf and H. A.
Khan
Department of Veterinary Microbiology,University
of Agriculture, Fasialabad, Pakistan
Abstract
A total of 200 chicks were
raised upto 43 days of age under controlled experimental conditions. The birds
were randomly divided into four groups A, B, C and D of 50 birds each at the age
of day one. Birds of groups A and B were not supplemented with selenium, while
those of groups C and D were given selenium @ 0.06 mg/Kg of feed from day one to
day 43. The birds of groups B and D were vaccinated against infectious bursal
disease (IBD) at the age of day 10 and boosted at the age of day 25. The effect
of selenium on humoral immune response was evaluated by recording weekly serum
antibody titres against IBD through indirect haemagglutination (IHA) test. The
cumulative mean titres (CMT) recorded in groups A, B, C and D were 15, 53, 16
and 61, respectively (P<0.05). These results indicate that selenium
supplementation may help to increase post vaccination humoral immune response
against IBD in broiler chicks.