PAKISTAN
VETERINARY
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INVESTIGATION OF THE TOXICITY POTENTIAL OF TRIGONELLA FOENUM GRAECUM (LINN)
K.D. Effraim, T.W. Jaxks and P.A. Nwafor 

Department of Pharmacology, College of Medical Sciences, University of Maiduguri, Maiduguri, Borno State, Nigeria

Abstract   

Extract prepared from the seeds of Trigonella foenum graecum Linn, was administered twice a week for four weeks, at dosages of 1.0, 1.5 and 2.0 gkg-1 body weight, to male albino Wistar rats. At the end of fourth week, the animals were sacrificed by transaction of the jugular vein and testes, kidneys and liver of each rat were processed for histopathological assessment. The extract of Trigonella foenum gruecum at all dose levels, had necrotic effect on the liver and the kidney tissues. Spermatogenesis was observed in the testes at dosage levels of 1.5 gkg-1 and 2.0 gkg-1 of the extract.    

 
 
   

ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)



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