Abstract   

The effect of Doxin on the serum biochemical and enzymic values of broiler chickens was studied. A total of 150 one day-old broiler chicks were randomly divided into six equal groups, A through F, each containing 25 birds. Group A and B were kept as control i.e, A was non medicated (Doxin) and vaccinated against Newcastle disease (ND) while B was non medicated (Doxin) and vaccinated against ND. Groups C and E were given Doxin at different levels (0.5 gm/i and 4 gm/i) from 1 to 5 day and 22 to 26 day respectively, but both groups were non vaccinated against ND. The experimental period was 42 days. Serum total protein, albumin (A), globulin (G), A/G ratio, uric acid, urea, alkaline phosphatase, alanin amino transferase and aspartate amino transferase levels were observed. The data obtained indicated that the mean levels of serum total protein and albumin of control and medicated groups were not significantly different from each other. The mean levels of globulin, A/G ratio of vaccinated and non vaccinated groups carry stati significant difference. The mean levels of urea and uric acid were increased in the medicated groups and highest in the double dose medicated groups. There was no significant difference in alkaline phosphatase (ALP), alanine amino transferase (ALT) and asparate amino transferase (AST) levels of all medicated and non medicated groups. Doxin proved to be a safe drug in broiler chickens.