CUTANEOUS PAPILLOMATOSIS IN HORSES: RESPONSE OF HORSES TO AUTOGENEOUS WART
VACCINE
Falah K. Al-Ani, Odeh F. A1-Rawashdeh, Nabil K. Hailat and Au Shotar
Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine,
Department of Pathology and Forensic Medicine, Faculty of Medicine,
University of Science and Technology, Jordan
Abstract
Cutaneous papillomatosis is usually regarded as benign epithelial tumor caused
by pipalioma virus. The condition is species specific and has the tendency to
spread frequently. In this study, a total of 15 horses suffered from cutaneous
papalloma were used to study the efficacy of the autogeneous papilloma vaccine.
Each horse was examined clinically and few wart lesions were removed surgically
and divided into two portions. One portion was fixed in 10% butTered neutral
formaline for histopathological studies. The second portion was submitted for
autogenous papilloma vaccine preparation. A total of 13 horses proved to be
infected with cutaneous papilloma received three doses of 0.5 ml on weekly
intervals intradermally. Two other horses with cutanesous pappillama were left
with no vaccine to serve as control. Results indicated that all horses received
the vaccine were free from papilloma lesions 3-5 weeks following the last dose
of the vaccine whereas the control groups remained infected