IMMUNO-MODULATORY EFFECT OF INACTIVATED EIMERIA
TENELLA VACCINE AND LIVE IMPPORTED COCCIDIAL VACCINE ON NEWCASTLE DISEASE VIRUS VACCINATED BROILER
CHICKS
Muhammad Akram Muneer, Haji Ahmad Hashmi, Masood
Rabbani, Zahid Munir Chaudhry and Ali M. Bahrami
Veterinary Microbiology Section,
College of
Veterinary
Sciences,
Lahore,
Pakistan
Abstract
A total of 160 one-day-old broiler chicks were
used to evaluate the immunomodulatory effects of an inactivated Eimeria tenella
vaccine and a live polyvalent imported antiococcidial vaccine (Coccivac). This
study indicated that both of these vaccines did not adversely affect the
development of serum antibody against
Newcastle
disease virus (NDV) and the chicks vaccinated with either of the anticoccidial
vaccines resisted the virulent NDV challenge. A study of the lymphoid organs
such as bursa of fabricuis: thymus and spleen from the experimental chicks
indicated that those organs were comparable with those from the chicks not
vaccinated with these coccidial vaccines. The overall findings of this study
indicate that anticoccidial vaccines do not have any effects on the immune
functions of the vaccinates. In fact these vaccines prevented the occurrence of
clinical coccidiosis in the vaccinates.