TOXICO-PATHOLOGICAL EFFECTS OF FORMALIN (37%
FORMALDEHYDE) FEEDING IN BROILER CHICKS
A. M. Babar, M. Z. Khan, Shabbir Ahmad1,
A. Khan, H. A. Bachaya and M. I. Anwar
Department of Veterinary Pathology.
University of
Agriculture. Faisalabad-38040,
Pakistan; 1Deparlment
of Pathology, Microbiology & Immunology.
University
of
California,
DavisCA95616,
USA
Abstract
One hundred day-old broiler chicks kept in five
equal groups (A-E) were given formalin (37% formaldehyde} at dose levels of 20,
10, 5, 2.5 and 0 ml/kg feed for 7 weeks. Body weight and feed intake of the
birds fed 2.5 ml formalin/kg feed was non-significantly different from control
whereas higher formalin levels groups had significantly lower values. Formalin
at 2.5 and 5.0 ml/kg feed level did not produce clinical signs in the birds but
Higher doses of formalin resulted in depression, somnolence and a staggering
gait. Necrotic and ulcerative areas on the mucosa of crop, proventriculus and
petechial hemorrhages were observed on the mucosa of small intestine. Liver and
kidneys did not show any specific microscopic changes. The no observed adverse
effect level (NOAEL) of formalin appeared to lie between 2.5 and 5 ml/ kg feed.