EFFECTS OF
IMMUNOSTIMULANTS ON BROILERS SUFFERING FROM INFECTIOU: BURSAL DISEASE
F.
Mushtaq, S. A. Khan, A. Aslam, K. Saeed1, G. Saleem and H. Mushtaq
Department of Pathology, 1Department of Parasitology, University of
Veterinary and Animal Sciences, Lahore, Pakistan.
Abstract
This
project was aimed to evaluate immunostimulatory effects of three therapeutic
substances in broilers suffering from infectious bursal disease (IBD). For this
purpose, 150 chicks were divided into five equal groups i.e. A, B, C, D and E
having 30 birds each. Group A, B, C and D were challenged with infectious bursal
disease virus. There were three immunostimulatory treatments i.e. levamisole
(group A), vitamin E (group B), and bursinex (group C). Groups D and E were
untreated control. Bursa body weight index, histopathology of bursa of Fabricius,
plasma cell counting in Harderian gland and estimation of antibody response
against infectious bursal disease virus was recorded. Vitamin E played a major
role in improving the condition of birds suffering from infectious bursal
disease, as it showed increased bursa body weight index (BBIx), less
histopathological lesions in bursa of Fabricius, increased number of plasma
cells in Harderian gland and high antibody response in infectious bursal disease
infected broilers as compared to levamisole and bursinex. Levamisole played a
minor role in improving condition of birds, while bursinex did not seem to be
much effective against infectious bursal disease virus in this study.