SEDATIVE AND ANALGESIC EFFECTS OF DETOMIDINE HYDROCHLORIDE IN GOATS
A. N.
Tunio., A. B. Kalhoro and I.H. Kathio1
Department of Surgery and Obstetrics, SindhAgricultureUniversity, Tandojam, Pakistan. 1Pittston AnimalHospital, PittstonPa, 18640, U.S.A.
Abstract
The sedative and analgesic effects of
three dose rates of detomidine (40, 50 and 60µg/kg body weight) were studied in
six goats. Moderate to deep sedation occurred after administration of 40µg/kg of
detomidine as compared to deep sedation produced by 50 and 60µg/kg of detomidine.
The degree, onset and duration of sedation and onset and duration of maximum
sedation were all dose dependent. Skin analgesia and recumbency were produced in
all animals with higher doses (50 and 60µg/kg) and in three animalswith lower dose (40µg/kg). Durationofrecumbencywas22.66 ± 1.45, 35.16 ±
1.68 and 55.66 ± 1.64 minutes after administration of 40, 50 and 60µg/kg of
detomidine, respectively.