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SEDATIVE AND ANALGESIC EFFECTS OF DETOMIDINE HYDROCHLORIDE IN GOATS

A. N. Tunio., A. B. Kalhoro and I.H. Kathio1

Department of Surgery and Obstetrics, Sindh Agriculture University, Tandojam, Pakistan.
1Pittston Animal Hospital, Pittston Pa, 18640, U.S.A.

Abstract

    The sedative and analgesic effects of three dose rates of detomidine (40, 50 and 60µg/kg body weight) were studied in six goats. Moderate to deep sedation occurred after administration of 40µg/kg of detomidine as compared to deep sedation produced by 50 and 60µg/kg of detomidine. The degree, onset and duration of sedation and onset and duration of maximum sedation were all dose dependent. Skin analgesia and recumbency were produced in all animals with higher doses (50 and 60µg/kg) and in three animals  with lower dose (40µg/kg). Duration  of  recumbency   was  22.66 ± 1.45, 35.16 ± 1.68 and 55.66 ± 1.64 minutes after administration of 40, 50 and 60µg/kg of detomidine, respectively. 

Key words: Goat, detomidine, sedation, dose response, analgesia.

 
   

ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)



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