EFFECT OF POST VACCINATION MEDICATION ON LAYER CHICKS VACCINATED WITH GUMBORO
VACCINE NOBILIS D-78
S.A.
Khan, S.M. Subtain, A. Aslam, K. Muhammad1 and K.A. Khan
Department of Pathology, 1Department
of Microbiology, University
of Veterinary
and Animal Sciences, Lahore,
Pakistan
Abstract
One hundred and sixty one-day-old layer chicks were divided into four
experimental groups A, B, C and D, with 40 birds in each group. Group A was kept
as control (non-vaccinated), group B was given vaccine but not medicated, group
C was administered vaccine as well as multivitamins for 3 days post-vaccination,
while group D was also medicated with aspirin for 3 days post-vaccination. The
parameters studied were: heterophil/lymphocyte ratio, serum biochemical analysis
(serum protein, glucose and cholesterol), antibody response against infectious
bursal disease virus (IBDV). At the end of experiment (42nd day) adrenal glands
from 10 randomly selected birds from each group were subjected to gross and
histopathological examination and adrenal/body weight ratio was also determined.
The results showed non significant
difference among different groups. However, the group that was given
multivitamins showed maximum immune response against IBDV, while the aspirin
therapy did not show any significant difference.
It can be concluded that vaccine produced undetectable stress in layer chicks
and the vitamin supplementation evidently showed as an immuno-potentiating
effect.