A study was carried out to determine the point prevalence of various helminths of cattle and buffalo population of district Toba Tek Singh, Pakistan and economic benefits of deworming with Oxyclozanide. Out of 540 fecal samples examined, 205 (37.96%) were found infected with helminths. Significantly higher (OR=2.2; P<0.05) prevalence of helminths was recorded in buffaloes (40%; 112/280) as compared to cattle (35.77%; 93/260). Oesophagostomum, Cooperia, Trichostrongylus, Strongyloide, Ostertagia, Fasciola (F.) hepatica, F. gigantica and Haemonchus contortus were the helminth species identified in the study area. Oxyclozanide medicated buffaloes (E=96.66%) and cattle (E=95.64%) showed a significant decrease in fecal egg counts on day 14 post-treatment. An average daily increase of 0.89 and 0.71 liters of milk along with 0.42 and 0.37% more fat per buffalo and cattle, respectively was observed in Oxyclozanide medication. The economic value of reduced production of infected animals was estimated as US$ 0.47 (Pak Rupees 40) and US$ 0.41 (Pak Rupees 35) per animal per day for cattle and buffaloes, respectively. It can be concluded that single dose of Oxyclozanide is effective against all bovine helminths.

Key words: Cost benefit analysis; Helminths; Oxyclozanide; Pakistan