Dexmedetomidine Related Bradycardia Leading to Cardiac Arrest in a
Dog
C. Y. Chen2, K-S. Chen1,2,
K. M. Chang2, W. M. Lee1,2, S. C. Chang1,2
and H. C. Wang1,2
1Department
of Veterinary Medicine, College of Veterinary Medicine; 2
Veterinary Medicine Teaching Hospital, College of Veterinary
Medicine, National Chung-Hsing University, 250-1 Kuo Kuang Road,
Taichung 402, Taiwan, R.O.C.
*Corresponding author: hcwang@dragon.nchu.edu.tw
Abstract
A 2-year-old, mixed breed female dog (16 kg) underwent an exploratory laparotomy
following ultrasonographic diagnosis of foreign body and a segment of small
intestine intussusceptions. The patient was classified as an ASA II. Ketamine
(1mg/kg, IV), and dexmedetomidine (2.5 µg/kg, IV), and morphine (0.6 mg/kg, SC)
were given as anesthetic premedication. Propofol (0.1 mg/kg, IV) titrated to a
total amount of 4 ml (2.5 mg/ kg) was given for intubation. Asystole was
occurred. Cardiac resuscitation was then conducted immediately. Atipamezole (0.1
ml) was injected, but showed no response on ECG. Atropine (0.02 mg/kg) was then
injected, and a second dosage was given. Two-three mins later, the heart rate at
84 beats/min. The NIBP showed 203/132 with MAP 153 mmHg, and the SpO2 showed 95%
after the cardiac function was regained. Dexmedetomidine related bradycardia
leading to cardiac arrest has been suggested in this case.
Key words:
Bradycardia, Cardiac arrest,
Dexmedetomidine,
Dog