Clinico-Hematological Disparities Induced by
Triazophos (Organophosphate) in Japanese quail
Abdul Ghaffar1, Sana Ashraf1,
Riaz Hussain2*,
Tanveer Hussain3, Maryam Shafique1,
Sobia Noreen1 and Sana Aslam1
1Department
of Life Sciences; 2University College of Veterinary and
Animal Sciences; 3Department of Forestry and Wildlife,
University College of Agriculture and environmental Sciences, The
Islamia University of Bahawalpur, Pakistan;
*Corresponding author:driazhussain@yahoo.com
Abstract
The present experimental study was conducted to determine
the clinico-hematological changes induced by oral administration of triazophos
in male Japanese quail. A total of 60 mature male quail were procured and
randomly divided into five equal groups. All the experimental birds received
triazophos orally @ 0, 2, 4, 6 and 8 mg/kg/day for 48 days. Birds were killed at
day 16, 32 and 48 for collection of blood. Various clinical signs like ruffled
feathers, tremors, watery droppings, salivation, torticollis, less foam
production, decreased frequency of crowing and mating with their pen mates were
observed at high doses (6 and 8 mg/kg/day triazophos). Significantly (P<0.05)
lowered feed intake and body weight was recorded. Overall significantly (P<0.05)
decreased total erythrocyte counts, total leukocyte counts, hemoglobin
concentration, mean corpuscular hemoglobin concentration while increased pack
cell volume and mean corpuscular volume was recorded in treated birds. It was
concluded that triazophos induces clinico-hematological changes including anemia
(macrocytic hypochromic) at higher doses in birds.