PAKISTAN
VETERINARY
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Serum Potassium-Lowering Effects of Insulin Plus Dextrose and Adrenalin Treatment that Enhance Intracellular Potassium Transitions in Hyperkalemic Diarrheic Calves
 
N Altuğ1, *, N Yüksek2, C Özkan2, Y Başbuğan2, İ Keleş3, ZT Ağaoğlu4, A Kaya2 and Y Akgül2
 
1Department of Internal Diseases, Faculty of Veterinary Medicine, University of Namık Kemal, 59030, Tekirdağ, TURKEY; 2Department of Internal Diseases, Faculty of Veterinary Medicine, University of Yuzuncu Yil, 65080, Van, Turkey; 3Department of Internal Diseases, Faculty of Veterinary Medicine, University of Erciyes, 38090, Kayseri, Turkey; 4Department of Internal Diseases, Faculty of Veterinary Medicine, University of Cumhuriyet, 58140, Sivas, Turkey; *Corresponding author: nurialtug@gmail.com
 

Abstract   

The study examined the serum potassium-lowering effects of different treatment options for hyperkalemia in diarrheic calves (n=18). Calves were allocated into three treatment groups. All groups received isotonic sodium bicarbonate solution for a period of 90 minutes. The animals in group 1 received no further treatment, those in group 2 received a further dose of 50% dextrose and insulin, and those in group 3 received a further dose of adrenaline. High serum K levels in all groups significantly decreased after treatment (AT) than before treatment (BT). Serum potassium levels AT in groups 2 and 3 were found to be significantly lower than those in group 1. Increase in pH, bicarbonate and total carbon dioxide values were observed AT in all groups. However, bicarbonate and total carbon dioxide levels in the AT were not statistically significantly different from those in the adrenaline group compared with the groups 1. These parameters were significantly lower in the group 2. Moreover, the concentration of glucose in the groups 2 in contrast to the adrenalin group was higher than that in both the BT and group 1 AT. The insulin + dextrose combination and adrenaline applications in hyperkalemic calves had similar effects. However, the administration of adrenaline had a lower negative effect on metabolic acidosis treatment.

Key words: Adrenaline, Calf, Diarrhoea, Hyperkalemia, Insulin, Treatment

 
   

ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)



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