Jiangxi Provincial Key Laboratory for Animal
Health, Institute of Animal Population Health, College of Animal
Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Economic and
Technological Development District, Nanchang 330045, Jiangxi, P. R.
China *Corresponding author:
hgljx3818@163.com
Abstract
Our goal was to study
the effects of Chinese herbal
products on the
lipid metabolism levels of Dongxiang blue-shelled layers (DBS). One hundred
healthy 22-week-old layers were randomly divided into 3 groups: control,
traditional
Chinese herbal product1 (TCM1) and traditional Chinese herbal product 2 (TCM2) groups.
The two TCM groups were treated with the Chinese herbal prescription products 1
and 2. Samples were collected on the 1st, 15th, 30th,
45th, and 60th day after TCM treatments. The blood samples
were tested using an automatic biochemical analyzer and the liver samples were
analyzed using real-time quantitative polymerase chain reaction. The results
showed that the levels of total cholesterol (TC), triglycerides (TG) and
low-density lipoprotein-cholesterol (LDL-C) were lower, whereas the levels of
high-density lipoprotein-cholesterol (HDL-C) were higher (P<0.05)
in the TCM treatment groups. Compared to the control group, the liver fat rate
in the TCM1 and TCM2 groups was significantly lower. Meanwhile, fat rate of
crureus and pectorals, and liver index were also lower than in the control
group. There was a significant decrease in cholesterol contents of the eggs. The
abdominal fat rate in the two treatment groups was lower than that of the
control group. The expression level of apolipoproteinA I and apolipoproteinB 100 in
the livers of the TCM1 and TCM2 groups increased; however, this increase was not
significant for the in apolipoproteinB 100 levels. In conclusion, the TCM
prescriptions have positive effects on the regulation of lipid metabolism
through a reduction in the cholesterol levels of eggs and the upregulation of
apolipoproteinA I and apolipoproteinB 100 mRNA
expression levels of in the liver.