Patho-Morphological Valuation of Acute Infection
of Brucella melitensis in
Goats
Asim Shahzad1, Du Xiaoxia2,
Ahrar Khan1,2,*, Muhammad Zargham Khan1,
Muhammad Saqib1, Shafia Tehseen Gul1, Muhammad
Kashif Saleemi1 and Jiang Bayi2,*
1Facultyof Veterinary Science, University of Agriculture,
Faisalabad-38040, Pakistan; 2Shandong Vocational Animal
Science and Veterinary College, Weifang 261061,China *Corresponding author:ahrar1122@yahoo.com (AK); sdmyxyjby@163.com (JBY)
Abstract
Brucellosiscaused by
Brucella melitensis is an important
zoonotic disease in the world. Brucella
melitensis is the causative organism of caprine and ovine brucellosis
characterized by abortion, retained placenta, orchitis which may induce
infertility, epididymitis and rarely, arthritis in small ruminants. However,
these lesions were regarded as chronic while acute patho-morphological lesions
had not been described in goats earlier. This study investigates the
histopathological lesions in organs of native goats of Pakistan acutely infected
by Brucella melitensis. Grossly, granulomatous lesions and edema were
observed in the lungs of the infected animals. Other organs including liver,
spleen, heart and spleen showed no gross lesions during necropsy. Severe
histological lesions were observed in the lungs and uterus of acutely infected
goats. The organism was detected by PCR from liver, lungs, spleen, uterus, sub
mandibular lymph nodes and bronchial lymph nodes. The organism was not detected
by PCR from the kidneys, ovaries, mammary glands, supra mammary lymph nodes,
internal ileac lymph nodes and scapular lymph nodes. It was concluded that
Br. melitensis acute infection did not lead to clinical presentation, although
the organism was well distributed in various organs of goats. The lesions were
generalized, not limited to reproductive organs.
To Cite This Article:
Shahzad A, Xiaoxia D, Khan A, Khan MZ, Saqib M,
Gul ST, Saleemi MKand Bayi J, 2018. Patho-morphological valuation of
acute infection of Brucella melitensis
in goats. Pak Vet J, 38(4): 341-346. http://dx.doi.org/10.29261/pakvetj/2018.099