This article highlighted the female reproductive problems associated with chronic diabetes and beneficial effects of camel’s milk on the gravid uterus of induced diabetic rats. Effects on the liver and kidney of neonatal rats were also observed. Eighteen female rats were divided into 3 groups: Group A was normal. Diabetes was induced with Alloxan^® in group B (diabetic control) and C (treated with camel milk @ 40 ml/kg/day for 98 days). On day 60, one adult male was introduced in each group for mating. Fortnightly blood glucose was monitored. Animals were slaughtered postpartum to collect blood for hematology, maternal uterus and liver and kidneys of their neonates. Paraffin embedding technique was used to prepare tissue sections, followed by H&E staining. Slides were examined to measure: uterine epithelium height, endometrial glands and thickness of myometrium. Significant (P<0.05) reduction was observed in hematological values of Group B in comparison to Group A. These parameters were significantly (P<0.05) improved by camel milk treatment. Blood glucose level of Group B was seen significantly (P<0.05) elevated than that of Group A. Camel milk treatment reduced blood glucose level significantly (P<0.05) at 4^th week and so on. Diabetes had showed significantly (P<0.05) detrimental impact on uterine histometrical parameters and camel milk therapy had significantly (P<0.05) reversed these changes towards the normal. Same trend was seen in neonate’s liver and kidneys. These findings suggest that camel’s milk reduces consequences of diabetes on maternal uterine and neonatal liver and kidney. Moreover, it improves the body weight of neonates delivered by camel milk treated diabetic mothers.

To Cite This Article: Ateeq MK, AS Qureshi, M Usman, RU Shahid and WA Khamas, 2019. Effect of orally administered camel milk in alloxan® induced albino rats: long term study on maternal uterus and neonates selected organs. Pak Vet J, 39(1): 81-85. http://dx.doi.org/10.29261/pakvetj/2018.114