Using Roquefortine C as a Biomarker in Hay for
Penitrem A Intoxication in a Beef Herd
F Bonelli1,2, V Meucci1, L
Turini1,2* and M Sgorbini1,2
1Department
of Veterinary Sciences, University of Pisa, Viale delle Piagge 2,
56124, Pisa, Italy
2Centro di Ricerche Agro-Ambientali “E. Avanzi”,
University of Pisa, via Vecchia di Marina 6, 56122, San Piero a
Grado (PI), Italy;
*Corresponding author:
luca.turini@phd.unipi.it
Abstract
Fifteen grazing beef cattle and calves presented
a history of neurological signs like ataxia, intentional head tremors, muscle
twitching. Nervous ketosis, nervous BVD, BHV-1,5, tremorgenic intoxication from
hay, and Listeriosis were considered as differential diagnosis. Blood samples
were collected. Inspection of hay bales showed large white dusty and moldy
areas. Samples were taken and analyzed. Altered hay was immediately removed in
all animals’ stock. No alterations were found in blood tests. Food analysis
showed high concentrations of Roquefortine C (RC) (345 μg/kg DM). Tremorgenic
syndrome has been reported in Penitrem A (PA) intoxication, but PA is difficult
to isolate in laboratory conditions. Both RC and PA are produced by
Penicillum spp. RC has been associated
with PA in tremorgenic toxicosis in dogs and it might be considered a valuable
diagnostic marker for PA intoxication. The neurological signs were due to
tremorgenic intoxication after feeding of spoiled forage contaminated with
mycotoxins.
To Cite This Article: Bonelli F, Meucci V, Turini L and Sgorbini M,
2020. Usingroquefortine c as a
biomarker in hay for penitrem a intoxication in a beef herd. Pak Vet J, 40(1):
136-138. http://dx.doi.org/10.29261/pakvetj/2019.112