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Molecular Detection and Clinical Aspects of Feline Herpesvirus-1, Feline Immunodeficiency Virus and Feline Leukemia Virus in Cats in Istanbul, Turkey

Erhan Bayraktar1,2 and Huseyin Yilmaz3*

1Department of Microbiology, Veterinary Faculty, University of Istanbul-Cerrahpasa, Avcilar, Istanbul, Turkey
2Ceva Animal Health, Büyükdere Caddesi, Izgiz Plaza, Maslak, Istanbul, Turkey
3Department of Virology, Veterinary Faculty, University of Istanbul-Cerrahpasa, Avcilar, Istanbul, Turkey
*Corresponding author:


The aim of this study was molecular detection of FIV, FeLV and FHV-1 and determination of frequency of these infections in cats and evaluation of clinical signs and status of the animals. For this, 30 household cats and 30 stray cats were clinically examined and blood samples and eye-swabs were taken. Samples were analysed by ELISA and PCR. In ELISA, 4 of 60 cats were positive for FIV and 6 of 60 for FeLV. FIV proviral-DNA was detected in 6 of 60 cats and FeLV proviral-DNA in 11 of 60 cats by PCR. Also, FHV-1-DNA was detected in eye swabs in 26 cats out of 60 cats. Clinically, eye disorders, ulcers in oral mucosa and respiratory disorders were observed in FIV, FeLV and FHV infected cats. Eye disorders were mostly seen in FHV-1 positive cats while fever was prominent in FeLV and FHV infected cats. The results show that FIV, FeLV and herpesvirus-1 are affecting the cat’s health and can make them susceptible to other pathogens which increase the risk of cat’s life.

To Cite This Article: Bayraktar E and Yilmaz H, 2020. Molecular detection and clinical aspects of feline herpesvirus-1, feline immunodeficiency virus and feline leukemia virus in cats in Istanbul, Turkey. Pak Vet J, 40(2): 249-252.


ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)