Anthrax has recently re-emerged worldwide, is a notifiable zoonotic disease with a high disease burden in Türkiye. Despite its importance for public health and the economy, little is known about the seasonal and spatiotemporal patterns of anthrax in animals. Therefore, seasonal and spatiotemporal patterns of livestock anthrax were evaluated in this study. At the provincial level, cartographic maps showing the distribution of anthrax outbreaks and cases were created. The spatial autocorrelation function (Moran's I) was employed to assess the spread features of outbreaks and the cluster locations were determined using LISA, Getis-Ord GI*. Using the Chi-square test, proportions of anthrax were calculated, along with their corresponding 95% confidence intervals. Monthly outbreaks were analyzed by the TRAMO/SEATS methods. The anthrax cases exhibited a positive spatial correlation and especially significant clusters were detected in Eastern Anatolia region. Years, regions, species and season were significantly associated with anthrax (P<0.001). Between 2005 and 2019, the most outbreaks (160, 10.36%) were recorded in 2018, while the most cases (1702, 15.92%) were recorded in 2005. When evaluated regionally, the highest rate of outbreaks (705, 45.66%) and cases (4539, 42.47%) were recorded in the Eastern Anatolia region. Additionally, the highest rate of outbreaks (631, 40.87%) and cases (4537, 42.45%) were recorded in the summer season. When evaluated in terms of species, the highest number of cases (5314, 49.72%) were recorded in cattles. The outbreak series were decomposed by the TRAMO/SEATS method and it was determined that there was a seasonal effect. When the outbreaks were evaluated on a monthly basis, it was observed that the outbreaks peaked in August (296, 19.17%). In conclusion, the anthrax in Türkiye has been characterized significantly seasonal and spatiotemporal. The disease pattern and obtained findings will contribute in the prevention and control of the disease.