Infectious bursal disease (IBD) or Gumboro disease is caused by the genera Avibirnavirus and the family Birnaviridae. For the last 66 years, this disease has been causing huge morbidity and mortality leading to huge economic losses throughout the world. For this review, we collected data from PubMed, CNKI, and Google Scholar, especially for the last decade. Articles containing significant information were thrashed, extracted, and information being presented. IBD virus (IBDV) could be attenuated, virulent (vIBDV), and very virulent (vvIBDV).  The host range is very wide including chickens, turkeys, Baltic ducks, pigeons, speckled pigeons, Herring gulls, ostriches, pied cordon blues, laughing doves, Antarctic penguins, and sparrows. The incubation period is very short, i.e., 2-3 days. The virus occurs worldwide, and prevalence varies from 8 to 100%. IBDV has a great affinity with lymphatic tissues. This disease is characterized by lesions of bursal hemorrhagic and inflamed lesions followed by atrophy thus leading to immunosuppression. Effective vaccination programs and strict biosecurity measures are mandatory for its prevention and control. The starring role of wild birds in the epidemiology of the IBD needs to be clarified as wild birds have indirect or direct contact with commercial chicken rearing. We concluded that infectious bursal disease is still a havoc in the poultry industry throughout the world. Vaccination is a successful tool to control and inhibit IBD. Vaccination failure could occur; however, farmers' education is necessary for successful vaccination and disease prevention/control.