Non-invasive radiographic techniques have emerged as essential tools in detecting, diagnosing, and treating malignant tumors in humans and animals. These techniques provide precise and accurate therapeutic responses with minimum side effects compared to surgical and conventional techniques. This review article focuses on advanced techniques including proton beam therapy, heavy ion therapy, high-intensity focused ultrasounds (HIFU), intensity modulation radiotherapy (IMRT), and image-guided radiotherapy (IGRT) and their effective and targeted use against superficial and deep organs including brain, bone, breast, liver, spleen, prostate and renal tumors in both humans and animals. These techniques are very effective and accurate in tumor destruction while minimizing damage to healthy tissues. Their effectiveness is enhanced when combined with advanced imaging techniques and other chemotherapeutic drugs. During the past decades, the application of modern radiographic techniques has been growing globally and frequently expanding for the treatment of various malignancies. However, due to cost-effectiveness and a very complicated structure, these therapies are not easily approachable. The effectiveness of these techniques can further be modified by using nanotechnology, artificial intelligence, and machine learning to make it more precise and economical.

To Cite This Article: Alshomrani F, 2025. Non-Invasive radiographic techniques in diagnosing and treating malignant tumors in animals and humans: Current Trends and Future Directions. Pak Vet J. http://dx.doi.org/10.29261/pakvetj/2025.124