Fasciolosis is an important parasitic disease of sheep and goats. This systematic review and meta-analysis summarized published prevalence estimates and explored geographic, diagnostic, and ecological variations. Five literature sources were searched for peer-reviewed reports published from 2002 to 2025, with findings synthesized separately for each host. Pooled prevalence was 15.3% in sheep and 10.4% in goats, but the prediction intervals were wide, and the evidence base was unevenly distributed across regions. Antibody detection, antigen detection, fecal egg examination, and post-mortem inspection measure different aspects of exposure or infection and therefore require separate interpretation. Substantial between-study variation and differences in sampling units limit the interpretation of the global summaries. The pooled values should be regarded as descriptive summaries of the available evidence rather than as uniform local risks. The findings support standardized diagnostic reporting and locally representative surveillance within region-specific One Health strategies.

To Cite This Article: Villa-Mancera A, Robles-Robles JM, Olivares-Pérez J, Olmedo-Juárez A, Córdova-Izquierdo A, González-Garduño R, Ponce-Covarrubias JL, Rivero-Perez N, Patricio F, Campos-García H, Cruz-Aviña JR and Ortega-Vargas S, 2026. Global prevalence of fasciolosis in sheep and goats: A Systematic Review and Meta-Analysis of epidemiological patterns, diagnostic methods, and climate-associated variation. Pak Vet J, 2026, 46(10): 2352-2368. http://dx.doi.org/10.29261/pakvetj/2026.237