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COMPARATIVE IMMUNE RESPONSE OF BROILER CHICKS TO NEWCASTLE DISEASE VACCINE (LASOTA STRAIN

M. Shuaib, M. Ashfaque, Sajjad-ur-Rahman, M.K. Mansoor and I. Yousaf1

Department of Veterinary Microbiology, 1Department of Clinical Medicine and Surgery, University of Agriculture, Faisafabad-38040, Pakistan

Abstract

    An experimental study was designed to asses the humoral and cell mediated immune response in the broiler chicks double vaccinated against Newcastle disease (ND) using Lasota strain of ND virus vaccine. Double vaccination 7 days following Ist vaccination gave haemagglutination inhibition (HI) titers ranging from 1:16 to 1:128, that was significantly higher than the HI antibody titer recorded after single vaccination. Similarly, macrophage migration inhibition (MMI) activity ranged from 28.57 to 40.86%, with mean activity of 36.07%. No correlation was found between HI titer and MMI test.

Key words: Haemagglutination, Newcastle disease vaccine, macrophage migration, broiler chicks.

 
   

ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)



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