Relationships Between Thyroid Hormones, Serum
Trace Elements and Erythrocyte Antioxidant Enzymes in Goats
S. Nazifi*, A. Shahriari1
and N. Nazemian2
Department of Clinical Studies, School of
Veterinary Medicine, Shiraz University, Shiraz, Iran; 1Department
of Basic Sciences, School of Veterinary Medicine, Shahid Chamran
University, Ahvaz, Iran; 2School of Veterinary Medicine,
Shahid Chamran University, Ahvaz, Iran; *Corresponding author:
nazifi@shirazu.ac.ir
Abstract
Healing effects of propolis and silver sulfadiazine (SS) on skin wounds in rats
were compared using qualitative and quantitative parameters and
histopathological findings. A total of 30 full thickness skin wounds were
created on dorsal aspects of 10 rats; i.e., three wounds on each rat. Of these
wounds, 10 each were allocated to group A (propolis), group B (SS) and group C
(control). The skin wounds in the rats of groups A, B and C were covered daily
for 14 days with 50% propolis cream, SS skin cream and bepanthane cream
(control),
respectively. Postoperatively, the wound surfaces were examined macroscopically
and the healing process and the rates of wound expansion, contraction and
epithelialization processes were quantitatively analyzed. As a result, propolis
was found in general to have a better wound healing effect than others. At the
10th day of experiment histopathologically, there was inflammatory
reaction with infiltration of lymphocytes, macrophages and neutrophils and
proliferation of fibroblastic loose connective tissue in dermis of rats of all
groups. The severity of these changes was lower in propolis treated group
compared to other two groups.