Twenty four Anatolian Black cows with primary ketosis (PK) and 10 clinically healthy cows (considered as control) were used in the study. The clinical, haematological, serum biochemical and cytogenetical parameters of all the animals were measured. Primary clinical signs included diminished appetite, decreased milk production, loss of weight, firm faeces and depression. Although no significant differences were seen with regard to haematological findings between PK and the control groups, significance increases (P<0.05) in aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT) and urea concen- trations were observed in PK group compared to the control group. Glucose concentration was significantly low and reversely correlated to ketone bodies in urine in the PK group, but it was within normal limits in the control group. GTL- banded karyotypes of the animals were obtained using the standard karyotype of Bos taurus. Chromosomal complements were 2n = 60 in Anatolian Black cattle of normal and diseased groups. In the light of these molecular cytogenetic data, it was detected that all the autosomal chromosomes were acrocentric and gonosomal chromosomes were submetacentric. The results of the study showed that no morphological differences occured in chromosomes in cattle suffering from PK.

Key words: Anatolian Black cattle, Chromosome morphology, Serum biochemistry, Primary ketosis