previous page   Pak Vet J, 2012, 32(2): 251-254   next page
 
Changes in Serum Acute Phase Reactants, Inflammatory Mediators and Gangliosides in Japanese quail (Coturnix japonica) with Retained Yolk Sac
 
N. Mosleh, S. Nazifi* and A. Alaeddini
Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz 71345-1731, Iran
*Corresponding author: nazifi@shirazu.ac.ir

Abstract   

Twenty-two 2-week-old Japanese quails (Coturnix japonica) with retained yolk sac have been assessed using validated standard procedures to quantify the serum concentration of the acute phase reactants (haptoglobin and serum amyloid A), inflammatory mediators (tumor necrosis factor-alpha, gamma interferon) and gangliosides (total sialic acid, lipid bound sialic acid and protein bound sialic acid). The present findings show that the concentrations of all measured parameters in diseased birds were significantly higher than the control group. Inflammation following yolk sac infection/retention leads to stimulation of the synthesis of inflammatory mediators, acute phase reactants and gangliosides. Among the study variables, lipid bound sialic acid had the most obvious change, so it is the most sensitive parameter.

Key words: Acute phase reactants, Gamma interferon, Gangliosides, Japanese quail, Tumor necrosis factor-alpha, Yolk sac retention

 
   

ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)



scopus
 
DOI
 
DOAJ SEAL