Changes in Serum Acute Phase Reactants, Inflammatory Mediators and
Gangliosides in Japanese quail (Coturnix japonica) with
Retained Yolk Sac
N. Mosleh, S. Nazifi* and A. Alaeddini
Department of Clinical Studies, School of Veterinary Medicine,
ShirazUniversity,
Shiraz71345-1731, Iran
*Corresponding author: nazifi@shirazu.ac.ir
Abstract
Twenty-two 2-week-old Japanese quails (Coturnix japonica) with retained
yolk sac have been assessed using validated standard procedures to quantify
the serum concentration of the acute phase reactants (haptoglobin and serum
amyloid A),
inflammatory mediators (tumor necrosis factor-alpha, gamma interferon) and
gangliosides (total sialic acid, lipid bound sialic acid and protein bound
sialic acid).
The present findings show that the concentrations of all measured parameters
in diseased birds were significantly higher than the control group. Inflammation
following
yolk sac infection/retention
leads to stimulation of the synthesis of inflammatory mediators,
acute phase reactants
and gangliosides. Among the
study variables,
lipid bound sialic acid had the most obvious change, so it is the most sensitive
parameter.