Impact of Different Levels of Silver Nanoparticles (Ag-NPs) on
Performance, Oxidative Enzymes, and Blood Parameters in Broiler
Chicks
Farhad Ahmadi
Sanandaj Branch, Islamic Azad University, Sanandaj, Iran
Corresponding author: k_a183@ymail.com
Abstract
This research was carried out to investigate the effects of Nano-silver (Ag-NPs)
on traits of productivity, oxidative stress state and some of blood Parameters
in broiler chicks. A total of 240, one-day-old male broiler chicks (Ross 308)
were allocated in a completely randomized design into four groups containing 60
birds, four replicates and 15 birds in each experimental pen. Basal diet
supplemented with different levels of Ag-NPs (Diameter 14±0.8 nm) was given
throughout research (1-42 days). Experimental diets included: 0 (Control), 20,
40, and 60 ppm Ag-NPs/kg diet. At the end of study period, one bird with closest
weight to the mean of any treatment was selected. Blood samples were collected,
centrifuged and removed serum stored at -20°C until analysis. Then birds
slaughtered and spleen, thymus, and bursa of Fabricius removed and their
relative weights calculated. The results showed that nano-silver has no
significant effect on growth performance but a decrease was found in feed
efficiency. Relative bursa weight had significantly decreased in compared with
control treatment (P<0.05). Lowest weight among treatments observed in treatment
that supplemented with 60 ppm nano-silver. Ag-NPs had significantly effected on
oxidative stress enzymes activity among treatment in comparison to control group
(P<0.01). Blood parameters such as ALT, AST, ALP, TP, Albumin, Gama globulin,
triglyceride, and cholesterol were significantly affected by using nano-silver
in broiler chicks (P<0.05).