Histopathologic Comparison of Radiofrequency and Scalpel Blade on
Mice Skin Incisional Wound Healing Model
Banafshe Gholamhoseini*, Soroush Mohitmafi1, Payam
Razeghi Tehrani2 and Sattar Noorialeagha3
Department of Pathobiology, 1Department of clinical
studies, Veterinary Faculty, Karaj branch, Islamic Azad University,
Karaj; 2Department of Anatomy and embryology, Veterinary
Faculty, Science and Research branch, Islamic Azad University,
Tehran; 3Veterinary Faculty, Karaj branch, Islamic Azad
University, Karaj, Iran
*Corresponding author email: drbhoseini@yahoo.de
Abstract
Using a safe and accurate
alternative to scalpel blades for various surgical operations has been more
considering today. There are many studies about the healing process of various
tissues after using different methods like radiofrequency, electro surgery and
scalpel blade for the surgical incisions, but choosing the right instrument is
very important in cosmetic surgeries.
This study was undertaken to get more histopathologic details about the healing
process after using either Radiofrequency (RF) or Scalpel blade as a skin
incision method. So, an experimental study was designed in that 12 mice were
randomly divided in three groups with the same situation and two different
incisions were cut in each mouse on ventral skin by scalpel blade and radio
surgical equipment. The skin specimens from scalpel blade incision as group one
sample and radiosurgical incision as group two sample were harvested on the same
operation day and a weekly manner to day 21.All samples were stained with Hematoxillin - Eosin and observed under
light microscopy. Results showed less tissue contraction at the cutting edge and
better collagen alignments in RF incision in comparison to scalpel blade
incisions in which having fibrosis and more tissue contraction. These
histopathologic findings might be the reason for more elasticity and less scar
tissue remaining after skin Radiofrequency surgery.