Polymorphic sites within a Bov-A2 element in the promoter region of the steroid 21-hydroxylase gene in cattle
Magdalena Jedrzejczak
West Pomeranian University of Technology,
Laboratory of Molecular Cytogenetics, Doktora Judyma 10, Szczecin
71-460, Poland.
*Corresponding author: mjedrzejczak@zut.edu.pl
Abstract
SINE elements are frequently studied in the
context of their location, evolution and hypothetical functions. In the present
paper, the T→C transition at nucleotide position 1564 located within the Bov-A2
SINE element in the promoter region of the
CYP21 gene was investigated in seven cattle breeds including Polish Holstein-Friesian, Jersey, Montbeliard, Charolais,
Angus, Hereford and Limousin. The
frequency of homozygotes (AA) and
heterozygotes (AB) was similar for the
Polish Holstein-Friesian breed, whereas a complete monomorphism was found in Jersey cattle. Moreover, only two genotypes (AA and AB) were observed
in Limousins. For the remaining breeds, the frequency of
homozygotes (AA) was the highest ranging
from 0.680 for Charolais to 0.865 for Montbeliard.