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Modern Approach to the Enigma of Bovine Respiratory Disease Complex: A Review
Vladimir S. Kurćubić1*, Radojica D. Đoković1, Zoran Ž. Ilić2, Jovan S. Stojković2, Milan P. Petrović3 and Violeta Caro-Petrović3
1University of Kragujevac, Faculty of Agronomy, Cara Dušana 34, 32000 Čačak; 2University of Prishtina-Zubin Potok, Faculty of Agriculture, Jelene Anžujske bb, Zubin Potok; 3Institute for Animal Husbandry, Belgrade-Zemun, Autoput 16, P.O. box 23, 11080 Zemun, Republic of Serbia.
*Corresponding author:


Research on Bovine Respiratory Disease Complex (BRDC) has strongly contributed to a better understanding of disease at both global and local levels. New agents have been identified and their nature has been better known since then, as well as all the factors that predispone the development of BRDC. Serious work in a number of researches has led to results that have proven significant synergistic interactions between viruses and bacteria that lead to the BRDC and complicate the prevention and treatment of the diseased cattle. Nowadays, it is necessary to apply the latest molecular and other techniques in order to examine in detail all of the specific causes, describe them accurately and provide effective prevention. This can primarily be accomplished by producing different types of vaccines, which are to be improved constantly. Serious progress has been made in researches on immunogenic properties and antimicrobial activity of various natural and synthetic substances in order to improve the production of more effective vaccines for control, as well as the development of a new generation of antibiotics to treat the disease. BRDC prevention programs have been successful, in which great importance was given to proper vaccinations and herd management practices. BRDC is still the most important disease of cattle from an economic point of view, since it causes great losses and expenses.

Key words: Bovine respiratory disease, complex, Diagnostic techniques, Infective agents, Medications, Vaccines


ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)