Modern Approach to the Enigma of Bovine
Respiratory Disease Complex: A Review
Vladimir S. Kurćubić1*,
Radojica D. Đoković1, Zoran Ž. Ilić2, Jovan S.
Stojković2, Milan P. Petrović3 and Violeta
Caro-Petrović3
1University of Kragujevac, Faculty of Agronomy,
Cara Dušana 34, 32000 Čačak; 2University of
Prishtina-Zubin Potok, Faculty of Agriculture, Jelene Anžujske bb,
Zubin Potok; 3Institute for Animal Husbandry, Belgrade-Zemun,
Autoput 16, P.O. box 23, 11080 Zemun, Republic of Serbia.
*Corresponding author:
vladevet@tfc.kg.ac.rs
Abstract
Research on Bovine Respiratory Disease Complex (BRDC) has
strongly contributed to a better understanding of disease at both global and
local levels.New agents have been identified and their nature has been
better known since then, as well as all the factors that predispone the
development of BRDC. Serious work in a number of researches has led to
results that have proven significant synergistic interactions between viruses
and bacteria that lead to the BRDC and complicate the prevention and treatment
of the diseased cattle. Nowadays, it is necessary to apply the latest molecular
and other techniques in order to examine in detail all of the specific causes,
describe them accurately and provide effective prevention. This can primarily be
accomplished by producing different types of vaccines, which are to be improved
constantly. Serious progress has
been made in researches on immunogenic properties
and antimicrobial activity of various natural and synthetic substances in order
to improve the production of more effective vaccines for control, as well as the
development of a new generation of antibiotics to treat the disease.BRDC prevention
programs have been successful, in which great importance was given to proper
vaccinations and herd management practices.BRDC is still the most important disease of
cattle from an economic point of view, since it causes great losses and
expenses.