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Uveodermatologic Syndrome in a Siberian Husky: Clinical and Histopathological Findings
Min-Hee Kang, Hyun-Jeong Sung, Dae-Young Kim1 and Hee-Myung Park*
Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 143-701, South Korea; 1Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, MO 65205, USA
*Corresponding author:


A 2-year-old, intact male Siberian Husky was presented with corneal opacity, eye lid swelling, depigmentation, alopecia and erythema predominantly on face. Bilateral uveitis preceded periocular and nasal planum depigmentation. Ancillary tests excluded other systemic diseases. Histopathology of the skin revealed lichenoid interface dermatitis with pigmentary incontinence. Diffuse pyogranulomatous inflammation of the globes was also noted. Based on the clinical signs and characteristic histopathological findings, the dog was diagnosed as uveodermatologic syndrome (UDS). Further treatment was not attempted in this case and the dog was euthanized. This case report describes typical clinical and histopathologic features of UDS in a Siberian Husky.

Key words: Dog, Depigmentation, Uveitis, Uveodermatologic syndrome, Vogt-Koyanagi-Harada syndrome


ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)