A 10-year-old male Golden Retriever was presented to the clinics with a history of  lameness. The radiography revealed granulomatous proliferation on caput femoris. Therefore, caput femoris was surgically removed and samples taken from the excised area were histologically examined.  Histologically, osteomyelitis was the prominent picture accompanied by large areas of granulomatous inflammatory cells expanding from the articular cartilage into the epiphysis of the bone and at these inflammatory areas cryptococci were visible within the macrophages.

Key words: Cryptococcus, Dog, Granulomatous osteomyelitis