PAKISTAN VETERINARY JOURNAL

Pak Vet J, 2014, 34(2): 270-272

Tubulopapillary Adenocarcinoma of the Mammary Gland in an Amazon Jaguar (Panthera onca)

Sung-ho Yun§, Chun-ho Park^1§, Hwan-soo Jang², Sae-kwang Ku³, Kwang-ho Jang and Young-sam Kwon*

Department of Veterinary Surgery, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea; ¹Department of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, 23-35-1 Higashi, Towada, Aomori 034-8628, Japan; ²Department of Pet Management, Suseong College, Daegu 708-711, Korea; ³Department of Anatomy and Histology, College of Oriental Medicine, Daegu Haany University, Daegu, 712-715, Korea. *Corresponding author: kwon@knu.ac.kr

Abstract

A 17-years-old, female Amazon jaguar (Panthera onca) was presented for a subcutaneous mass of the mammary gland. Surgical excision and microscopic examination of the mass was performed. Histopathologically, the mass was uncapsulated and composed of tubulopapillary lobules of atypical round to polygonal epithelial cells. Tumor cells showed invasive growth into the connective tissue of the dermis and mitotic figures were frequently observed. Tumor cells also showed diffusely strong positive for cytokeratin (CK) AE1/AE3, proliferation cell nuclear antigen (PCNA) and Ki-67 antibodies. But, CK14, vimentin and P63 immunoreactivity was mainly expressed in the myoepithelial cell layer. Based on these pathological findings, present case was diagnosed as tubulopapillary adenocarcinoma of the mammary gland of Amazon Jaguar (Panthera onca).

Key words: Adenocarcinoma, Jaguar, Mammary gland

Abstract

ISSN 0253-8318 (Print)ISSN 2074-7764 (Online)

ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)