Antimicrobial Activity of
Copaifera langsdorffii Oil and Evaluation of its Most Bioactive
Fraction against Bacteria of Dog’s Dental Plaque
FA Pieri1,2,3, VO Silva1,
FS Vargas3, VF Veiga Junior3 and MAS Moreira1*
1Bacterial
Diseases Laboratory, Sector of Preventive Veterinary Medicine and
Public Health, Veterinary Department, Federal University of Viçosa;
Av. P.H. Rolfs, s/n, CEP: 36570-000, Viçosa, MG, Brazil; 2Leônidas
and Maria Deane Institute, Oswaldo Cruz Foundation. Rua Terezina,
476, Adrianópolis, CEP: 69.057-070, Manaus, AM, Brazil; 3Exact
Sciences Institute, Federal University of Amazonas. Av. Rodrigo
Otávio, 6200, Coroado, CEP: 69.080-005, Manaus, AM, Brazil *Corresponding author: masm@ufv.br
Abstract
The aim of this study
was to evaluate the inhibitory effect of copaiba oil and its resinous and
volatile fractions against 20 bacterial isolates from dental plaque of dogs. The
antimicrobial activities of the oil and its fractions were evaluated by the agar
diffusion test with solutions at 10% concentration. The results showed
antimicrobial activity for the copaiba oil solution on 16 isolates. The volatile
fraction was considered statistically similar (P>0.05) to copaiba oil intact on
the size of inhibition zones inhibiting 17 isolates. The resinous fraction
inhibited only eight isolates, with smaller haloes when compared with those of
the volatile fraction and intact oil (P<0.05). It is concluded from these
results that copaiba oil is a potential phytotherapic to be used in dental
plaque antimicrobial therapy of dogs and suggests that its activity is due to
sesquiterpenes of the volatile fraction.