Influence of Dietary Supplementation with
Selenium on Blood Metabolic Profile and Thyroid Hormones Activities
in Fattening Lambs
Z Antunović1*, J Novoselec1,
M Šperanda1, T Klapec2, S Ćavar3, B
Mioč4, Ž Klir1, V Pavić5 and R
Vuković5
1Faculty
of Agriculture, University of Josip Juraj Strossmayer in Osijek, K.
Petra Svacica 1 d, 31000 Osijek, Croatia; 2Faculty of
Food Technology, University of Josip Juraj Strossmayer in Osijek,
Kuhaceva 18, 31000 Osijek, Croatia; 3Institute of Public
Health for Osijek-Baranya County, F. Krezme 1, 31000 Osijek,
Croatia; 4Faculty of Agriculture, University of Zagreb,
Svetosimunska cesta 25, 10000 Zagreb, Croatia; 5Department
of Biology, University of Josip Juraj Strossmayer in Osijek, C.
Hadrijana 8/A, 31000 Osijek, Croatia *Corresponding author: zantunovic@pfos.hr
Abstract
The aim of the investigation was to determine
influence of dietary supplementation with selenium on blood metabolic profile
and thyroid hormones activities in fattening lambs. The study included 36 Merinolandschaf lambs during
fattening period (50 days) divided
into three groups (control, Exp-I and Exp-II). The
control group diet was not supplemented with Se, whereas the diet of Exp-I was
supplemented with 0.3 mg/kg inorganic selenium (sodium selenite) and Exp-II with
0.3 mg/kg organic selenium (Sel-Plex). Concentration of minerals (Ca,
P-inorganic, K, Na, Fe and Cl), biochemical indicators (urea, glucose,
cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, creatinine, total
protein, albumin), enzyme activity (ALT, AST, GGT, LDH and GSH-Px) and thyroid hormone activities (T3, T4)
were determined.
Significantlyhigher (P<0.01)
selenium contentandGSH-Px
activity as well as the lowercontent ofCa was determined in the bloodof Exp-II and Exp-I groups
compared to control group (93.89 and 67.69: 34.11 µg L-1;
607.98 and 556.92: 247.52 µkat L-1; 2.38 and 2.39: 2.76 mmol L-1).
Significantlyhigher (P<0.01)
selenium contentin the in bloodof lambs from Exp-IIcompared toExp-I group was determined.
Significantlyhigher (P<0.05)
concentrations ofHDL-cholesterol
and T3hormoneactivity were found in Exp-II group
compared to theExp-Iand
control groups. The results showed lower blood selenium
content in control group and indicate thejustificationof addingselenium, especially organicseleniumin
lamb’s diets, raising the concentration of Se, GSH-Px enzyme,
HDL-cholesterol and T3 hormones improving the health status,
especially in areas deficientin
selenium.