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Korean Beechwood Creosote as a Substitute to an Antibiotic for Post Weaning Diarrhea in Piglets
Simrinder Singh Sodhi1, Jeong Hyun Kim1, Neelesh Sharma1, Kwang Keun Cho3, Jae Young Kim6, Ki Beom Kim4, Chul-Yon Jeong5, Yong Min Yoon2, Sung Jong Oh1 and Dong Kee Jeong1*
1Department of Animal Biotechnology, Faculty of Biotechnology, Jeju National University, Jeju, Korea; 2Department of Veterinary Medicine, College of Veterinary Medicine, Jeju National University, Jeju, Korea; 3Department of Animal Resources Technology, Gyeongnam National University of Science and Technology, Jinju, Korea; 4Korea Institute for Animal Products Quality Evaluation, Anyang, Korea; 5Changjobio Research Institute, Changjobio Corporation, Jeju, Korea; 6Swine Science & Technology Center, Gyeongnam National University of Science and Technology, Jinju, Korea
*Corresponding author:


Post weaning diarrhea (PWD) effects the economy of pig industry and extensive use of antibiotics to treat PWD led to the development of antibiotic resistance. To counter the issue of antibiotic resistance, role of Korean beechwood creosote has been studied. Six weeks old, 12 piglets were divided into four groups (3 in each). Diarrhea was induced with S. typhimurium in three groups. Piglets treated with creosote have shown 11.52 and 3.12% higher growth rate than control group (C2) and antibiotic treated groups respectively. Creosote treated group has shown 78% reduction in the fecal score of as compare to C2 on 5th day after induction. No negative impact is imposed by Korean beechwood creosote on hemogram. Significantly (P<0.05) high values of complete blood count (WBCs, RBCs, PCV, MCH and MCHC) have been observed in the diarrheic animals and persisted up to 10th day after induction whereas these parameters were in normal range in animals treated with creosote after recovery. Significantly (P<0.05) lower platelet count and total protein values have been observed in C2 as compared to treatment groups and similar decreasing trend has been observed for albumin, globulin and A:G ratio. The blood urea nitrogen (BUN) levels in treatment groups were in normal range while it was significantly higher in C2. Significantly low and high values of sodium (Na+) and potassium (K+) respectively, have been observed in C2. Parallel findings between the antibiotics and Korean beechwood creosote strongly suggest its use as an antidiarrheal agent and growth promoter for weaning piglets.

Key words: Antibiotics, Blood chemistry, Hematocrit values, Korean beechwood creosote, Post weaning diarrhea


ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)