Kidney Myelolipoma and Amyloidosis Associated
with Lung Osseous Metaplasia in Broiler Chicken
Carmen Solcan, Florentina Bocaneti, Mircea
Fântânariu and Viorel Cezar Floristean*
Faculty of Veterinary Medicine, University of
Agricultural Sciences and Veterinary Medicine Ion Ionescu de la
Brad, Iasi, Romania;
*Corresponding author:
vfloristean@uaiasi.ro
Abstract
A case of renal myelolipoma and amyloidosis
associated with osseous metaplasia in a 14 day old broiler chicken in an
experimental group is described. Beginning with their 6th day of
life, forty broiler chickens (Ross 308) were randomly separated into two groups
of 20 subjects each. The experimental group was treated with ochratoxin A (OTA)
for 21 days (50 µg/kg/day) and the other one constituted the control group.
Histological examination of the kidney revealed a proliferation of mature
adipocytes, accumulation of numerous myelocytes, erythroblasts, eosinophilic
myelocytes and heterophils, delimited by an osseous tissue surrounded by renal
parenchyma. A similar ectopic metaplastic tissue was observed in the lungs.
Additionally, in kidneys, skin and liver an amorphous deposit of amyloid was
observed.