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Fatal Case of Clostridium difficile Infection in a Neonatal Piglet in Korea
Ha-Young Kim1,3, Byeong Yeal Jung1, Jae-Won Byun1, Kyung-Hyun Lee1, Ara Cho1, Myoung-Heon Lee1, J Glenn Songer2 and Bumseok Kim3,*
1Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency, 175 Anyang-ro, Manan-gu, Anyang 430-757, Korea; 2Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011 USA; 3Department of Pathology, College of Veterinary Medicine, Chonbuk National University, Jeonju 561-756, Korea
*Corresponding author:


There have been litters of neonatal piglets that died shortly after birth, with a fatality of nearly 100%. The submitted pig had pasty yellowish brown colonic contents and severe mesocolonic edema with distinct suppurative colitis and lymphadenitis. Clostridium difficile toxins were detected and heavy growth of toxigenic C. difficile was yielded in the colonic contents. This strain was characterized by ribotype 078 and had multidrug resistance. A fatal case of porcine enteritis associated with C. difficile in Korea has been described.

Key words: Clostridium difficile, Enteritis, Piglet, Toxin


ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)