Clinical and Histopathological Findings of Renal
Dysplasia in a Miniature Poodle Dog
Jae-Hee Cho, Seung-Gon Kim, Min-Hee Kang,
Chang-Min Lee, Won-Jung Kim, Doo-Won Song and Hee-Myung Park*
Department of Veterinary Internal Medicine, College of Veterinary
Medicine, Konkuk University, Seoul, 143-701, South Korea;
*Corresponding author: parkhee@konkuk.ac.kr
Abstract
An 18-month-old, spayedfemale, miniature
Poodle dog was presented forpreoperative evaluation of severe azotemia prior to surgical correction
of bilateral medial patellar luxation. On physical examination, the dog appeared
emaciated and less than 5%
dehydrated. Results of hematological analyses indicatedleukopenia,
azotemia, and hypercalcemia.
Additionally, urinalysis revealed proteinuria and low specific gravity
compatible with chronic kidney disease (CKD). Ultrasonographyshowed bilaterally small irregular kidneys.To make a definitive
diagnosis, renal biopsy was performed under the guidance of ultrasound.Histopathologyrevealeda high percentage of
fetal glomeruli, which was consistent with congenital renal dysplasia. This
case describes clinical and histopathological features ofcongenital
renal dysplasia diagnosed by percutaneous renal biopsy.