Role
of
Mannheimia (Pasteurella)
haemolytica in Severe Respiratory Tract Infection in
Commercial Poultry in Pakistan
Akbar Ali1*,
Naila Siddique1, Muhammad Athar Abbas1, Abdul
Ghafar1, Saba Rafique1, Riasat Ali2,
Ateeq-Ur-Rehman Memon3 and Khalid Naeem1
1National Reference Lab for
Poultry Diseases, Animal Sciences Institute, National Agricultural
Research Centre, Islamabad, Pakistan; 2Remount Veterinary
and Farms Directorate, GHQ, Rawalpindi, Pakistan; 3Pakistan
National Accreditation Council, Islamabad, Pakistan *Corresponding author:
akbaralimalik@ymail.com
Abstract
Mannheimia haemolytica is the causative agent of several economically
significant diseases of cattle and sheep, however, its role in causing infection
in poultry is limited as secondary pathogen, co-infecting with viral pathogens
like infectious bronchitis virus (IBV),
infectious laryngotracheitis virus (ILTV) etc. The present study reports
first time in this country regarding the isolation of M. haemolytica from
adult commercial poultry flocks, initially reported with severe respiratory
distress. Necropsy findings were quite similar to those found in Fowl cholera
infection. The samples were also processed for the detection of any avian
respiratory viruses in addition to testing for bacterial presence. The lab
investigations led to the detection of M. haemolytica from the clinical samples and
subsequent use of norfloxacin, selected on the basis of sensitivity pattern of
the organism, resulted in curing of the flock. To further confirm the pathogenic
potential of this organism, 7-day old broilers were challenged with the new
isolate. The bacterium M. haemolytica was subsequently recovered from the
birds which died within 3 weeks post-infection, confirming the pathogenic
potential of this organism in poultry. The drug susceptibility pattern of the
recovered bacterium was similar to the original isolate. This study further
identifies the role of different management factors leading to infection of
birds with M. haemolytica and suggests appropriate control measures in
poultry flocks.