The objective of this study was to examine the association between β-hydroxybutyrate (BHBA) and glucose, cobalt (Co), copper (Cu), manganese (Mn), magnesium (Mg), and phosphorus (P) in cows with clinical ketosis and control group. At the beginning; while serum glucose levels, Co, Cu, Mn, Mg and P concentrations in cows with clinical ketosis were lower, BHBA levels were higher than control group. At the 3^rd day after the treatment, serum Co, Cu, Mn and P concentrations were lower in cows with clinical ketosis than control group. According to these results, mineral level decrease was detected in cows with ketosis. It is thought that there should be more study performed about the contribution of minerals to the treatment of ketosis. This study will provide an insight to the studies will be performed in this respect.

Key words: Cow, Ketosis, Mineral substance