In human, mice and different veterinary species, T cells are subdivided into phenotypically different subpopulations based on their expressed T cell receptor and cell specific surface markers. As no data were available regarding the existence of T cell subpopulations in the peripheral blood of dromedary camels, the current study aimed at the identification of camel blood T cell subpopulations and the analysis of their adhesion molecules expression patterns. Using monoclonal antibodies cross-reactive with camel CD antigens, camel blood WC1-positive T cells and CD4-positive ab T cells and their expression pattern of adhesion molecules were identified by flow cytometry. Under camel CD4-positive T cells, a major fraction (83%) with naïve phenotype (CD4⁺ CD11a^lo CD44^lo) and minor fraction (13%) with effector phenotype (CD4⁺ CD11a^hi CD44^hi) were identified. In addition, the analysis of age related effects on the proportion of lymphocyte subsets indicates that camels belong to the T cell high species.

To Cite This Article: Hussen J, Shawaf T, Al-herz AI, Alturaifi HR, Al Khamees MH and Alluwaimi AM, 2018. Expression patterns of cell adhesion molecules on CD4⁺ T cells and WC1⁺ T cells in the peripheral blood of dromedary camels. Pak Vet J, 38(3): 231-236. http://dx.doi.org/10.29261/pakvetj/2018.055