1College
of Veterinary Medicine of Yunnan Agricultural University, Kunming,
Yunnan, 650201, China
2Center of endangered animal and plant rescue of
Kunming, Yunnan, 650200, China
*Corresponding author:
changhuaxx@126.com
Abstract
Klebsiella oxytoca is
one of the most common pathogens causing septicemia, pneumonia, and urinary
tract infections in humans and animals and is a major concern for public health.
In the present study, we aimed to elucidate the pathogenicity of
K. oxytoca isolates obtained from
Larus ridibundus using an
in vivo system. The results revealed
that the bacteria grew on EMB, lysogeny broth agar, MacConkey medium, nutrient
broth, sheep blood agar, and Salmonella
Shigella agar. K. oxytoca from
L. ridibundus showed highest similarity (96.6%) to the reference
strain (AB476819.1). Pathological biopsy revealed that
K. oxytoca severely damaged hepatocytes, renal tubular epithelial
cells, lymphocytes, and alveolar bronchioles in infected mouse tissues. The
presence of this pathogen in L. ridibundus suggested that infectious diseases may be transmitted
via pollution of water, allowing human infection to occur during the migration
process. The findings will provide the foundation for the studies on the
treatment of K. oxytoca.
To Cite This Article:
Chang H, Dai F, Duan G,
Zhao S, Lu HandXiang X, 2018.
Pathogenicity
Analysis of Klebsiella oxytoca
Isolated from Larus ridibundus
migratory birds. Pak Vet J, 38(4): 449-451. http://dx.doi.org/10.29261/pakvetj/2018.096