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Toxico-pathological Effects of Thiamethoxam on Hemato-biochemical and Productive Performance of Commercial Laying Hens
Shafia Tehseen Gul1, Ihtesham Ahamd1, Muhammad Kashif Saleemi1, Maqbool Ahmad1, Latif Ahmad2 and Ahrar Khan1,3*
1Faculty of Veterinary Science, University of Agriculture, Faisalabad, 38040, Pakistan
2Baqai College of Veterinary Sciences, Baqai Medical University, Karachi-75340, Pakistan
3Shandong Vocational Animal Science and Veterinary College, Weifang, China
*Corresponding author:


This study was planned to find out the hemato-biochemical effects of thiamethoxam (TMX) in the commercial layer. For this purpose, a total of 75 birds of 30 weeks age were purchased from a commercial farm. Birds were equally divided into five groups A, B, C, D and E. Standard housing conditions were provided to all birds by providing optimum temperature and humidity. Different dosages of TMX including 250, 500, 750 and 1000 mg/kg.bwt were administered to B, C, D and E, respectively. Group A served as control. The trial continued for 45 days that was the peak production period. All groups were monitored daily for physiological parameters including feed consumption, egg production, and eggshell thickness. Blood with and without anticoagulant was collected for hemato-biochemical parameters. Adverse effects on FCR and egg production were recorded in laying hens. Eggshell thinning was also evident. Anemia was a consistent finding in all the TMX treated groups. Physiological impairments of the liver and kidney biomarkers have also been recorded in treatment groups as compared to control. Thus, it can be concluded here that sub-lethal doses of TMX have adverse effects on production performance, hematology and biochemistry of the laying hens.

To Cite This Article: Gul ST, Ahamd I, Saleemi MK, Ahmad M, Ahmad L and Khan A, 2020. Toxico-pathological effects of thiamethoxam on hemato-biochemical and productive performance of commercial laying hens. Pak Vet J, 40(4): 449-454.


ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)