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First Comparative Biochemical Profile Analysis of Cystic Fluids of Taenia hydatigena and Echinococcus granulosus Obtained from Slaughtered Sheep and Goats
Mughees Aizaz Alvi1, Li Li1, Sami Ullah Khan Bahadur2, Muhammad Saqib3, John Asekhaen Ohiolei1, Rana Muhammad Athar Ali3, Imaad Rashid3, Khurram Ashfaq3, Asif Ali Butt4, Muhammad Zaeem Abbas5, Muhammad Haleem Tayyab3, Amjad Islam Aqib6, Warda Qamar7, Ali Hassan3, Anum Aizaz Alvi5, Azhar Aslam8, Bao-Quan Fu1, Hong-Bin Yan1* and Wan-Zhong Jia1*

1State Key Laboratory of Veterinary Etiological Biology, National Animal Echinococcosis Para-Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, People’s Republic of China; 2The Fleming Fund Country Grant Pakistan, DAI, Islamabad, 44000; 3Department of Clinical Medicine and Surgery, University of Agriculture, Faisalabad, Pakistan; 4Riphah University, Faisalabad, Pakistan; 5Independent Researcher, Faisalabad, Punjab, Pakistan; 6Department of Medicine, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan; 7Department of Parasitology, University of Agriculture, Faisalabad, Pakistan; 8Department of Microbiology, The Islamia University of Bahawalpur, Pakistan
*Corresponding author:;


The organic and inorganic constituents present in cystic fluid play a crucial role in the physiology, metabolism and immune responses mediated by taeniids. We designed a comparative study on T. hydatigena and E. granulosus cysts based on biochemical profile. In the present study, we aspirated fluid from Taenia hydatigena (n=30) and Echinococcus granulosus (n=30) cysts recovered from slaughtered sheep and goats in the central abattoir of Faisalabad, Pakistan. The fluid obtained from each cyst was subjected to biochemical analysis to estimate the levels of liver enzymes, electrolytes and selected biomolecules (proteins, glucose, cholesterol, urea, and creatinine). Thereafter, the student’s t-test was used to determine significant differences between constituents of the cystic fluids obtained from both type of cysts. The difference was considered statistically significant at P<0.05. The levels of total protein and globulin differed significantly (P<0.05) and were found to be higher in T. hydatigena cystic fluid. A non-significant difference was observed for albumin. Similarly, higher concentrations of electrolytes (sodium, chloride and magnesium) were observed in T. hydatigena cystic fluid with statistically significant difference (P<0.05). Concerning liver enzymes, high levels (p>0.05) of ALP and LDH were observed in T. hydatigena and E. granulosus cystic fluid had significantly higher (P<0.05) level of AST. The levels of cholesterol, urea and creatinine were higher in E. granulosus. In contrast, glucose was higher in T. hydatigena. A significant difference (P<0.05) was observed for these four biomolecules. Overall, these results suggest high variations of investigated biomolecules, liver enzymes, and electrolytes composition between cystic fluids of E. granulosus and T. hydatigena. Further studies are now warranted to set the standards for the differential diagnosis of cysticercosis and cystic echinococcosis based on cystic fluid contents.

To Cite This Article: Alvi MA, Li L, Bahadur SUK, Saqib M, Ohiolei JA, Ali RMA, Rashid I, Ashfaq K, Butt AA, Abbas MZ, Tayyab MH, Aqib AI, Qamar W, Hassan A, Alvi AA, Aslam A, Fu BQ, Yan HB and Jia WZ, 2022. First comparative biochemical profile analysis of cystic fluids of Taenia hydatigena and Echinococcus granulosus obtained from slaughtered sheep and goats. Pak Vet J, 42(2): 215-221.


ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)