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Epidemiological Study of the Co-infection of Immunosuppressive Poultry Pathogens in Tissue Samples of Chickens in Jiangsu Province, China from 2016 to 2022
Caihong Yan1, 2, Qi Zhong1, 2, Wenjie Jin1, 2, Yang Yang1, 2, Zhiqiang Wang1, 2 and Daxin Peng1, 2*

1Animal Disease Testing and Technical Service Center, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China; 2Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou 225009, China
*Corresponding author:


Chicken infectious anemia virus (CIAV), Marek’s disease virus (MDV), reticuloendotheliosis virus (REV), and avian leukosis virus (ALV) are immunosuppressive pathogens of concern for poultry. To investigate the prevalence of immunosuppressive pathogens in diseased chickens and the interactions between different viral infections, 768 tissue samples collected from diseased chickens in Jiangsu Province, China were analyzed for CIAV, MDV, REV, and ALV using polymerase chain reaction. The detection rate of these four immunosuppressive pathogens was 55.99%, and the detection rates of CIAV, MDV, REV, and ALV were 29.95, 23.05, 9.90 and 23.44%, respectively. The detection rates of coinfection, dual infection, triple infection, and quadruple infection were 23.57, 17.45, 5.47 and 0.65%, respectively. The most common dual and triple infections were CIAV + ALV (detection rate: 5.08%) and CIAV + MDV + ALV (detection rate: 2.60%). The infection of chicken flocks with immunosuppressive pathogens in Jiangsu Province showed a decreasing trend from 2016 to 2022. There was a synergistic association between CIAV and REV or CIAV and ALV (P<0.01). Therefore, infections and co-infections with immunosuppressive pathogens are prevalent in chicken flocks in Jiangsu Province, China, and CIAV plays a critical role in co-infection, providing an important guide for the future control of these diseases.

To Cite This Article: Yan C, Zhong Q, Jin W, Yang Y, Wang Z and Peng D, 2024. Epidemiological study of the co-infection of immunosuppressive poultry pathogens in tissue samples of chickens in Jiangsu Province, China from 2016 to 2022. Pak Vet J.


ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)