This study aimed to explore the magnetic resonance cholangiopancreatography (MRCP) manifestations of the pancreaticobiliary ducts and assess pancreatic exocrine function using Secretin-enhanced MRCP (S-MRCP) in dogs with acute edematous pancreatitis (AEP).  Twelve (12) dogs were included, with six in the AEP group and six in the control group. The AEP model group underwent a procedure by way of pancreatic duct retrograde injection. The control group underwent the same procedure without infusion. MRCP and S-MRCP were performed identically in both the AEP group and control groups. MRCP was performed pre-surgery and on the 1^st, 3^rd, and 5^th days post-surgery in the AEP group and control groups. The pancreaticobiliary duct diameter was significantly wider in the AEP group compared to the control group (P<0.01) on the 5^th day. The S-MRCP images were evaluated on the 3^rd day post-surgery at 1, 3, 5, 7, and 11 min after secretin infusion. Compared to the control group, the pancreatic ducts in the AEP group became dilated and branched which appeared, reaching the largest diameters, 3 min postsecretin injection (P<0.01). Eleven minutes after secretin infusion, the degree of duodenal filling in the AEP group was Grade 2, indicating impaired pancreatic exocrine function in dogs with AEP. In conclusion, MRCP provided excellent comprehensive visualization of the pancreatic and hepatobiliary duct systems in dogs with AEP. S-MRCP effectively detected branched pancreatic ducts and impaired pancreatic exocrine in AEP dogs.